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Meanwhile, MCF 7 Adr cells with YY1 knockdown were co transfected with miR 873 5p inhibitor and we found that miR 873 5p inhibitor rescued the inhibition of YY1 knockdown on stemness, PI3K AKT and ERK1 2 pathways, and adriamycin sensitivity, characterized as the increase of expression of stemness markers and re activation of PI3K AKT and ERK1 2 signaling Figure 8C, rescue of CD44 CD24 sub population Figure 8D, the capacity of cell spheroid the formation Figure 8E, and cell viability Figure S7H <